Description
BenzoNuclease is a genetically engineered endonuclease from Serratia marcescens.
BenzoNuclease acts as an endonuclease that degrades both DNA and RNA—whether single stranded, double-stranded, linear, circular or supercoiled. Upon complete digestion, all free nucleic acids present in solution are reduced to 5’-monophosphateterminated oligonucleotides, which are three to five bases in length.
BenzoNuclease is an efficient enzyme for removing all forms of DNA and RNA from biological products. In processed biological products, there may be traces of BenzoNuclease residues, and these traces of residues will have a certain impact on the application of subsequent biological products. The residual amount of BenzoNuclease in biological products is one of the important indicators to measure the quality of biological products.
This kit can detect and quantitatively analyze the BenzoNuclease residues in recombinant viral vectors and vaccine preparations with high sensitivity and specificity.
Reaction Principle
